Advancing the relevance of clinical trials for older patients
Listen to this summary
The authors aim to address the challenge of making clinical trials more relevant for older patients, a rapidly growing and diverse demographic with limited treatment evidence. They review best practices and successful strategies for improving trial inclusivity, selecting appropriate interventions, and focusing on meaningful outcomes, while highlighting the slow uptake of previous recommendations and the value of observational studies in complementing trial data.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.

More from Lancet (London, England)
View all →Jul 9, 2026 · Lancet (London, England)
Temocillin versus carbapenems for bacteraemia due to third-generation cephalosporin-resistant Enterobacterales in Spain (ASTARTÉ): a multicentre, phase 3, open-label, non-inferiority, randomised clinical trial
Jul 9, 2026 · Lancet (London, England)
Fixed-duration pirtobrutinib plus venetoclax-rituximab versus venetoclax-rituximab for patients with previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (BRUIN CLL-322): an open-label, multicentre, randomised, controlled, phase 3 trial
Jul 9, 2026 · Lancet (London, England)
Children in all policies: lessons from a global collaboration to promote the health and wellbeing of children and future generations
Jul 8, 2026 · Lancet (London, England)
Systemic light chain and transthyretin amyloidosis-treatment advancements and future directions
Jul 7, 2026 · Lancet (London, England)
Standard-dose unfractionated heparin versus low-dose unfractionated heparin and low-molecular-weight heparin in extracorporeal life support (RATE): an open-label, randomised, non-inferiority trial
Jul 6, 2026 · Lancet (London, England)
Inherited retinal degenerations: clinical phenotypes and emerging therapies
More in Nuclear Medicine
View all →Jul 8, 2026 · The New England journal of medicine
Ensartinib in Resected <em>ALK</em>-Positive Non-Small-Cell Lung Cancer
Jul 8, 2026 · The New England journal of medicine
Meningococcal B Vaccine to Prevent <em>Neisseria gonorrhoeae</em> Infection
Jul 8, 2026 · The New England journal of medicine
Nutrition Therapy in Critically Ill Adults
Jul 8, 2026 · The New England journal of medicine
Setmelanotide for the Treatment of Acquired Hypothalamic Obesity
Jul 3, 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Clinical Application and Research Advances of PET Molecular Imaging in Immune Checkpoint Inhibitor-Associated Myocarditis
Jul 2, 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Immuno-PET in Cardiovascular Disease: Advances, Challenges, and Opportunities
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR


