Temocillin versus carbapenems for bacteraemia due to third-generation cephalosporin-resistant Enterobacterales in Spain (ASTARTÉ): a multicentre, phase 3, open-label, non-inferiority, randomised clinical trial
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The study aimed to determine whether temocillin is non-inferior to carbapenems for treating bacteraemia caused by third-generation cephalosporin-resistant Enterobacterales (3GCR-E). The results indicated that temocillin achieved similar clinical success rates compared to carbapenems, supporting its use as an effective and safe alternative in this patient population.
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