Harnessing the oral microbiome in chronic liver disease: mechanisms, therapeutic modulation and translational frontiers

The authors investigate the role of the oral microbiome in advanced chronic liver disease (ACLD) and its implications for systemic inflammation and hepatic complications. They aim to highlight the mechanisms linking oral dysbiosis to liver injury and propose both immediate clinical practices and innovative therapeutic strategies to improve patient outcomes. The review seeks to synthesize current knowledge and identify gaps in understanding the oral-gut-liver axis, ultimately advocating for the integration of oral health into hepatology care.