April 20, 2026 · JAMA internal medicine · DOI: 10.1001/jamainternmed.2026.0844

Benefits and Harms of Dementia Screening for Family Members of Older Adults: A Randomized Clinical Trial

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This randomized clinical trial aimed to evaluate the benefits and risks of dementia screening for family members of older adults in primary care settings. The study found that screening did not lead to significant improvements in family members' health-related quality of life, caregiver preparedness, or caregiving self-efficacy, nor did it increase levels of depression or anxiety among family members. The low rates of positive screenings and high refusal rates for follow-up assessments may explain these findings.

Nicole R Fowler, Anthony J Perkins, Sujuan Gao, Tamilyn Bakas, Katharine J Head, Anna Higbie, Christina Baucco, Christopher M Callahan, Monica M Williams-Farrelly, Malaz A Boustani

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