Deprescribing Intervention and Reduction of Proton Pump Inhibitor Use in Primary Care: A Cluster Randomized Clinical Trial
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The authors aimed to evaluate the effectiveness of a deprescribing intervention designed for both patients and general practitioners (GPs) in reducing inappropriate use of proton pump inhibitors (PPIs) in primary care settings. The study found that the combined intervention led to a significant reduction in PPI use compared to usual care and a GP-only intervention, while having no meaningful impact on gastroesophageal reflux disease activity.
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