Abscopal effect following palliative radiotherapy after cemiplimab in recurrent cervical cancer: a case report

This case report investigates the occurrence of the abscopal effect in a patient with recurrent cervical cancer who received palliative radiotherapy following cemiplimab treatment. The authors aim to demonstrate how localized radiotherapy can induce regression of distant metastatic lesions, potentially enhancing systemic antitumor immunity in conjunction with immune checkpoint inhibitors. The findings suggest a promising synergy between radiotherapy and PD-1 blockade, warranting further research into mechanisms and treatment strategies to optimize this effect in advanced gynecologic cancers.