September 14, 2026 · Gynecologic oncology reports · DOI: 10.1016/j.gore.2026.102197

Real-world outcomes after Mirvetuximab Soravtansine treatment for recurrent ovarian Cancer: Results from a university setting

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The authors aimed to evaluate the real-world effectiveness and toxicity of Mirvetuximab Soravtansine (MIRV) in patients with recurrent ovarian cancer, as previous trials had stringent eligibility criteria. In a retrospective analysis of 66 patients, they found a median overall survival of 16.4 months and a progression-free survival of 5.3 months, with performance status significantly impacting survival outcomes. The study highlights the common occurrence of toxicity and the need for careful management, particularly in patients with poorer performance status.

Anna V Jones, Rachel L Furuya, L Stewart Massad, Dong Wang, Mary M Mullen, Brooke E Sanders

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