September 18, 2026 · American journal of obstetrics and gynecology · DOI: 10.1016/j.ajog.2026.09.019

Antihypertensive Treatment Escalation and Maternal Outcomes During Expectant Management of Early-Onset Preeclampsia With Severe Features

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The authors aimed to evaluate the relationship between the escalation of antihypertensive treatment and adverse maternal outcomes during the expectant management of early-onset preeclampsia with severe features. Their findings indicate that increasing the number of antihypertensive dose escalations is associated with a higher risk of maternal complications, suggesting that treatment escalation may reflect disease progression and could be a valuable factor in maternal risk assessment.

Yossi Bart, Zakaria Doughan, Laura Diab, Ahmed Salaheldin Zaki Moustafa, Baha M Sibai

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