The use of locoregional therapies in cholangiocarcinoma

This literature review investigates the role of locoregional therapies in managing unresectable or advanced cholangiocarcinoma (CCA), particularly intrahepatic (iCCA) and perihilar CCA (pCCA). The authors aim to evaluate the clinical outcomes of various locoregional treatments compared to the standard systemic chemotherapy and immunotherapy, highlighting the need for individualized treatment strategies until more robust evidence from randomized controlled trials is available. The findings suggest a trend towards integrating locoregional therapies with standard care to improve patient outcomes.