Mouse models of acute and chronic hepatitis E virus infection
Listen to this summary
The authors aimed to develop mouse models to study hepatitis E virus (HEV) infection, particularly focusing on the susceptibility of different mouse strains to HEV and the mechanisms underlying chronic infection. They successfully established AG129 and C57BL/6J mouse models that support efficient HEV-C1 replication, revealing important insights into viral tropism and the role of CD4+ T cell depletion in persistent infection. These models provide a valuable platform for further research on HEV immunopathogenesis, antiviral testing, and vaccine development.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from Journal of hepatology
View all →Sep 22, 2026 · Journal of hepatology
Restoration of aged liver regeneration by youthful systemic factors via LTβ-driven hepatocyte reprogramming
Sep 15, 2026 · Journal of hepatology
Systemic therapy for HCC: Doublets, triplets and beyond
Sep 15, 2026 · Journal of hepatology
Advances in the imaging of liver cancer
Sep 15, 2026 · Journal of hepatology
The use of locoregional therapies in cholangiocarcinoma
Sep 15, 2026 · Journal of hepatology
Liver transplantation for primary liver cancers in the era of transplant oncology
Sep 15, 2026 · Journal of hepatology
Integrating systemic therapy in the earlier stages of liver cancer
More in Internal Medicine
View all →Sep 23, 2026 · JACC. Clinical electrophysiology
Programmed Ventricular Stimulation for Risk Stratification in Nonischemic Cardiomyopathy With Preserved or Mildly Reduced LVEF
Sep 23, 2026 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Five-Year Follow-Up of the Phase III ASCOT Trial of Adjuvant S-1 After Resection for Biliary Tract Cancer
Sep 23, 2026 · American journal of respiratory and critical care medicine
Biologic outcomes in severe asthma patients by smoking status: evidence from SHARP
Sep 23, 2026 · The New England journal of medicine
Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis
Sep 23, 2026 · The New England journal of medicine
Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma
Sep 23, 2026 · American journal of respiratory and critical care medicine
Combined results of the TETON-1 and TETON-2 Trials of Inhaled Treprostinil for Idiopathic Pulmonary Fibrosis
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
