Predictive Value of Lipoprotein(a) and LPA Genetic Risk Score for Incident of Sudden Cardiac Death
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The authors aimed to investigate the relationship between serum Lipoprotein(a) levels and LPA genetic risk score with the risk of sudden cardiac death (SCD), while also examining how these associations vary by age, sex, triglyceride levels, and APOE genotypes. Their findings indicate that higher Lp(a) levels and LPA GRS are linked to an increased risk of SCD, particularly in older males with elevated triglycerides, with APOE genotypes influencing this risk. This research suggests that Lp(a) could serve as a valuable biomarker for SCD risk stratification and prevention.
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