Mayo Clinic proceedings
Audio Summaries

The Burden of Pancreatic Cancer in ASEAN Member States (1990-2023) and Future Trends Forecasting: A GBD 2023 Analysis

Sep 21, 2026

The authors aimed to characterize the trends, demographic influences, and socioeconomic disparities in the burden of pancreatic cancer across the 11 ASEAN member states from 1990 to 2023, while also projecting future trends through 2050. Their analysis revealed significant increases in incident cases, deaths, and disability-adjusted life years (DALYs), with notable variations among countries, indicating a need for tailored prevention and health-system strategies to address the rising burden of pancreatic cancer in the region.

Healthy Lifestyle, Genetic Susceptibility and Risk of Kidney Stone Disease in the UK Biobank: A Prospective Cohort Study

Sep 18, 2026

The authors aimed to investigate the relationship between modifiable lifestyle factors and the risk of kidney stone disease (KSD), as well as how genetic susceptibility influences this association. Their findings indicate that a healthy lifestyle significantly reduces the risk of KSD, and while no multiplicative interaction was found, an additive interaction suggests that individuals with an unfavorable lifestyle and high genetic risk have a markedly increased risk of developing KSD.

Incidence and Risk Factors for Severe Postoperative Hypotension in General Care Wards

Sep 2, 2026

The authors aimed to determine the incidence and predictors of severe postoperative hypotension (SPOH) in patients transferred to general care wards after surgery. They found that 0.7% of patients experienced SPOH, with significant predictors including lower body mass index, longer procedure duration, and intraoperative blood transfusion. The study emphasizes the importance of monitoring patients with low preoperative and postoperative blood pressure to mitigate the risk of SPOH.

Barriers and Facilitators to Innovation: A Qualitative Study in a Non-Profit Health Care System

Sep 1, 2026

The authors aimed to explore how users within a non-profit healthcare system perceive and engage with the organization's innovation management process, identifying barriers and facilitators to innovation participation. Through qualitative interviews, they found that barriers included fragmented pathways and siloed communication, while facilitators encompassed leadership support and collaboration. The study highlights the need for transparent innovation frameworks and supportive organizational culture to enhance innovation efforts and implementation.

Zephyr, Vega, Milo, and Bell: "Living" Art at Mayo: The Mayo Clinic Peregrine Falcon Program

Sep 1, 2026

The authors explore the integration of art within the Mayo Clinic environment, highlighting its historical significance since the completion of the original building in 1914. They aim to illustrate how art enhances the experience of patients and staff, as well as its role in the healing process. Each issue of the Mayo Clinic Proceedings features an artistic work, providing a platform for interpretation and appreciation of art in a healthcare setting.

Primary Care Management of Ileal Pouch Disorders: Diagnosis, Treatment, and Referral

Sep 1, 2026

The authors aim to address the primary care management of ileal pouch disorders, particularly focusing on the diagnosis, treatment, and referral processes for complications arising from ileal pouch-anal anastomosis (IPAA). They highlight the prevalence of pouchitis and other complications in patients with IPAA and emphasize the critical role of primary care clinicians in early recognition and management, as well as the importance of timely referral to specialists for more severe cases.

Frailty Attenuates the Prognostic Value of Multimorbidity in Heart Failure - Insights From the Largest Tertiary Center in the Middle East

Aug 31, 2026

The authors aimed to determine how frailty influences the relationship between multimorbidity and mortality in heart failure patients. Their findings indicate that while multimorbidity is associated with increased mortality risk, this association is significantly weakened in frail individuals, suggesting that frailty modifies the prognostic value of multimorbidity in heart failure.

Impact of a Nationwide Remote Patient Care Hypertension Program on Clinical and Health Care Cost and Utilization Outcomes

Aug 27, 2026

The authors aimed to evaluate the effectiveness of a remote patient care (RPC) hypertension program on improving clinical outcomes and reducing healthcare costs for Medicare patients with hypertension. The study found significant reductions in blood pressure and an increase in the percentage of patients achieving target blood pressure levels, alongside a decrease in total healthcare costs and inpatient admissions. Overall, the RPC program demonstrated a positive impact on hypertension management and healthcare utilization.

"You'll be Fine. Probably." Communicating Risk in Clinical Medicine

Aug 25, 2026

The authors investigate the challenges of effectively communicating risk in clinical medicine, aiming to understand how barriers such as linguistic ambiguities, numeracy issues, and emotional influences can lead to misinterpretation of risk information by patients. They propose a multifaceted approach to risk communication, including the use of descriptive terms, numerical data, and visual aids, while emphasizing the importance of tailoring discussions to individual patient understanding and values. The paper introduces the RISKS framework to enhance clinician-patient communication about risk.

The Optimal Timing for Patients With Acute Myocardial Infarction to Safely Undergo Elective Non-Cardiac Surgery: A Retrospective Cohort Study

Aug 20, 2026

The authors aimed to determine the optimal timing for elective non-cardiac surgery in patients who have experienced an acute myocardial infarction (AMI) to ensure safe postoperative outcomes. Their findings indicate that patients with a history of AMI within 12 months face significantly increased risks of complications and mortality, particularly if surgery occurs within one month post-AMI, with risks decreasing markedly after one year. The study suggests that the timing of surgery should be tailored to each patient's medical condition.