Acute Estimated Glomerular Filtration Rate Decline After Initiation of Therapies That Slow Kidney Disease Progression: Clinical Practice Implications
Listen to this summary
The authors investigate the implications of an acute decline in estimated glomerular filtration rate (eGFR) following the initiation of therapies aimed at slowing chronic kidney disease (CKD) progression in patients with type 2 diabetes. They find that while these therapies may cause an initial eGFR decline, this is typically reversible and linked to beneficial hemodynamic changes, suggesting that such declines should not deter treatment continuation. The review emphasizes that an acute eGFR decline of less than 30% is generally not indicative of adverse kidney effects and may even predict better long-term outcomes.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from Mayo Clinic proceedings
View all →May 8, 2026 · Mayo Clinic proceedings
Gut Oxalate Transport and Gut Microbiome as Potential Therapeutic Targets for Hyperoxaluria and Hyperoxalemia: Implications for Related Human Disease
May 7, 2026 · Mayo Clinic proceedings
Hybrid Quantum-Classical Model That Combines Spatial-Temporal EEG and Digitized Counterdiabatic Quantum Features for Motor Imagery Classification
May 2, 2026 · Mayo Clinic proceedings
Consensus Recommendation: Real World Insights on Attitudes and Treatment of Hyperkalemia
May 2, 2026 · Mayo Clinic proceedings
Resting Heart Rate is an Independent Prognostic Marker for Cancer Mortality and a Modifiable Target of Physical Activity: A Prospective Cohort Study From 615,730 Asian Participants
May 1, 2026 · Mayo Clinic proceedings
Heart Failure Phenotypes and the Prognostic Utility of NT-proBNP in Patients With Chronic Kidney Disease: A Propensity-Score Matched Cohort Study
May 1, 2026 · Mayo Clinic proceedings
On the Spectrum: High-Functioning Autism and Its Contemporary Relevance
More in Internal Medicine
View all →May 10, 2026 · JAMA
Digoxin in Patients With Symptomatic Rheumatic Heart Disease: A Randomized Clinical Trial
May 10, 2026 · European heart journal
Blinded withdrawal of randomized treatment with low-dose digoxin or placebo in patients with heart failure: the DECISION trial
May 10, 2026 · Lancet (London, England)
Endovascular thrombectomy for patients with large-core ischaemic stroke presenting up to 24 h after onset (ATLAS): a systematic review and individual patient data meta-analysis with central imaging adjudication
May 10, 2026 · European heart journal
Renin-angiotensin-aldosterone system inhibition and haemocompatibility-related adverse events in patients with durable left ventricular assist device: the MOMENTUM-3 trial
May 10, 2026 · JAMA
Efficacy and Safety of Digitalis Glycosides in Heart Failure: A Meta-Analysis
May 10, 2026 · Lancet (London, England)
Impact of introducing RTS,S/AS01<sub>E</sub> malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
