Heart Failure Phenotypes and the Prognostic Utility of NT-proBNP in Patients With Chronic Kidney Disease: A Propensity-Score Matched Cohort Study
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The authors aimed to assess the prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in predicting outcomes across different heart failure phenotypes in patients with chronic kidney disease (CKD). The study found that patients with heart failure with reduced ejection fraction (HFrEF) had higher NT-proBNP levels and an increased risk of all-cause mortality and major adverse cardiac events compared to those with heart failure with preserved ejection fraction (HFpEF), while NT-proBNP's predictive value for renal outcomes was limited.
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