May 1, 2026 · Mayo Clinic proceedings · DOI: 10.1016/j.mayocp.2026.02.016

On the Spectrum: High-Functioning Autism and Its Contemporary Relevance

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The authors examine the contemporary relevance of high-functioning autism, particularly in light of the DSM-5's reclassification of autism spectrum disorder, which has led to a significant increase in diagnosed cases. They aim to address the challenges faced by adults with high-functioning autism, including social and occupational difficulties, and emphasize the importance of recognizing and managing comorbid conditions while providing appropriate support services to enhance quality of life.

J Michael Bostwick, Alastair J S McKean

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