April 24, 2026 · Mayo Clinic proceedings · DOI: 10.1016/j.mayocp.2026.03.026

Traditional Risk Factors Provide Limited Insight Into Long-Term Cardiovascular Risk After Carotid Endarterectomy

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The authors aimed to determine the incidence of major adverse cardiovascular events (MACE) and identify long-term clinical predictors in patients with carotid artery disease following carotid endarterectomy (CEA). They found that traditional risk factors provided limited insight into the high incidence of MACE, highlighting the need for novel approaches to improve risk assessment and guide secondary prevention strategies in this patient population.

Ludovica Di Venanzio, Alessia Pinna, Negin Mahmoudi Hamidabad, Elizabeth A Copley, John C Benson, Luca Saba, Brad R Lewis, Arush Rajotia, Giuseppe Lanzino, Lilach O Lerman, Esther Lutgens, Amir Lerman, Valentina Nardi

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