July 22, 2026 · Mayo Clinic proceedings · DOI: 10.1016/j.mayocp.2026.02.017

Timing of Mechanical Circulatory Support and In-Hospital Mortality in Patients With Cardiogenic Shock

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The authors aimed to evaluate the impact of the timing of mechanical circulatory support (MCS) on in-hospital mortality in patients with cardiogenic shock. Their findings indicate that initiating MCS on the first day of admission is associated with a significant reduction in mortality compared to starting it on the second day, with consistent results across different types of devices and shock etiologies.

Sanjana Garimella, Cesar Caraballo, Angela M Victoria-Castro, Israel Safiriyu, Soumya Banna, Clancy W Mullan, Talal El Zarif, Santiago Callegari, Abdelrahman Abushouk, Mark Jacobs, Andrea Elliott, Jason N Katz, Ann Gage, Nihar R Desai, Tariq Ali, P Elliott Miller

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