July 22, 2026 · The New England journal of medicine · DOI: 10.1056/NEJMra2511692

Antiretroviral Therapy

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This article by Roy M Gulick reviews the advancements in antiretroviral therapy (ART) for HIV infection, focusing on the effectiveness of various drug classes in suppressing viral replication and improving patient outcomes. The authors aim to highlight the importance of ART in enhancing immune function, reducing morbidity and mortality, and preventing transmission, ultimately demonstrating that individuals on ART can achieve life expectancies comparable to the general population. The article also discusses the ongoing monitoring and adaptation of treatment regimens based on patient response and resistance testing.

Roy M Gulick

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