July 15, 2026 · The New England journal of medicine · DOI: 10.1056/NEJMoa2510881

Health Care-Associated Infections in U.S. Hospitals, 2023 versus 2015

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The authors aimed to assess changes in the prevalence of health care-associated infections (HAIs) in U.S. hospitals by comparing data from 2023 to previous surveys conducted in 2015. Their findings indicate a decrease in the prevalence of HAIs, with 2.6% of patients affected in 2023 compared to 3.2% in 2015, although the overall burden remains significant, with an estimated 518,000 HAIs in U.S. hospitals in 2023. Notably, a majority of these infections were not linked to medical devices or procedures.

Nora Chea, Rongxia Li, Taniece Eure, Rebecca Alkis Ramirez, Joelle Nadle, Jane E Lee, Monica Lehmann, Lyndzie Sardenga, Christopher A Czaja, Helen Johnston, Melissa Kellogg, Catherine Emanuel, Alana Cilwick, Maria A Correa, Meghan Maloney, Susan M Ray, Jessica Howard-Anderson, Stacy Carswell, Lucy E Wilson, Rebecca Perlmutter, Kaytlynn Marceaux-Galli, J P Mahoehney, Ruth Lynfield, Marla Sievers, Cory Cline, Melissa Judson, Ghinwa Dumyati, Christine Hurley, Elizabeth Keller, Marissa Walsh, Erin Licherdell, Julia Tellerman, Rebecca Pierce, Valerie L S Ocampo, Monika E Samper, Kimberly A Hires, Lauren T Adrian, Roza P Tammer, Alexia Zhang, Shannon Hiratzka, Angela Dusko, Christopher Wilson, Melphine Harriott, Henrietta Smith, Victoria Russo, LaTasha Boswell, Dominique Godfrey, Denise Leaptrot, Marissa McMeen, Melissa Otis, Jennifer Watkins, Amber Taylor, Rita Allen, Nicola D Thompson, Jonathan R Edwards, Shelley S Magill, Cheri T Grigg

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Health Care-Associated Infections in U.S. Hospitals, 2023 versus 2015

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