Quantitative MRI Assessment of Gyrification and Brain Volume in Congenital Cytomegalovirus Fetuses and Postnatal Outcome
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The authors aimed to quantitatively assess the impact of congenital cytomegalovirus (CMV) infection on fetal brain development by analyzing cortical gyrification and brain volumes in CMV-exposed fetuses, while also evaluating postnatal outcomes. Their findings revealed that CMV-infected fetuses exhibited reduced cerebral gyrification regardless of MRI findings, and follow-up indicated that some children experienced neurodevelopmental difficulties, highlighting the potential for improved risk identification through quantitative MRI analysis.
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