Genetic Etiology of Miscarriage in a Vietnamese Cohort Using CNV-Seq and Exome Sequencing
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This study investigates the genetic causes of pregnancy loss in a Vietnamese cohort, aiming to characterize the associated clinical features. Analyzing 636 cases, the authors found genetic abnormalities in 32.9% of cases, with numerical chromosomal abnormalities being the most prevalent. The findings suggest that the use of copy number variant sequencing and clinical exome sequencing can aid in identifying genetic factors contributing to pregnancy loss, potentially guiding future pregnancy management.
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