July 15, 2026 · The New England journal of medicine · DOI: 10.1056/NEJMcp2411656

Fibromyalgia

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The authors explore the characteristics and management of fibromyalgia, a condition marked by widespread pain, fatigue, and cognitive issues, often coexisting with other chronic pain disorders. They emphasize the role of the central nervous system in the condition's hyperresponsiveness to sensory stimuli and discuss how effective treatments aim to restore CNS balance. While fibromyalgia is rarely curable, the authors highlight that it can typically be managed effectively within primary care settings.

David A Williams, Daniel J Clauw

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