The impact of fresh versus cryopreserved testicular sperm on in-vitro fertilization outcomes in couples with elevated sperm DNA fragmentation: a retrospective cohort study
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This study aimed to compare the reproductive outcomes of fresh versus cryopreserved testicular sperm in couples with elevated sperm DNA fragmentation undergoing intracytoplasmic sperm injection (ICSI) after testicular sperm extraction (TESE). The authors found no significant differences in cumulative live birth rates, clinical pregnancy rates, miscarriage rates, fertilization, or blastocyst conversion between the two sperm types. They conclude that both fresh and cryopreserved testicular sperm yield similar outcomes, but suggest that further research with larger sample sizes is necessary to confirm these findings.
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