Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial
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The LatAm-FINGERS trial aimed to assess the feasibility and effectiveness of a culturally adapted, multidomain lifestyle intervention for preventing cognitive decline in at-risk older adults across 11 Latin American countries. The study found that this structured intervention led to greater improvements in cognitive function compared to a flexible health-advice intervention, highlighting its potential as a scalable strategy to address the rising dementia burden in low- and middle-income countries.
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