July 6, 2026 · JAMA · DOI: 10.1001/jama.2026.12038

Alcohol-Related Liver Disease: A Review

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The authors review the rising prevalence and impact of alcohol-related liver disease (ALD), aiming to highlight its progression, risk factors, and treatment options. They emphasize the importance of early diagnosis through noninvasive testing and the critical role of alcohol cessation in improving patient outcomes, particularly for those with severe forms of the disease. The paper also discusses the potential need for liver transplantation in cases of severe alcohol-associated hepatitis or decompensated cirrhosis.

Aleksander Krag, Fredrik Åberg, Jessica Mellinger, Brian P Lee, Mads Israelsen

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