Prone Positioning in Infants With Acute Bronchiolitis: The PROPOSITIS Randomized Clinical Trial
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The authors aimed to determine whether prone positioning in infants with moderate to severe acute bronchiolitis receiving high-flow nasal cannula (HFNC) support could reduce the need for escalation to noninvasive or invasive ventilation. In a multicenter randomized trial involving 451 infants, they found no significant difference in the escalation of care between those in the prone position and those in the supine position. The study suggests that while prone positioning did not show a definitive benefit, further research is needed due to the wide confidence interval around the results.
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