An AI-Based OCT System to Detect Diabetic Macular Edema: A Prospective Validation and Noninferiority Randomized Clinical Trial
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The authors aimed to evaluate the diagnostic and referral performance of an AI-based optical coherence tomography (AI-OCT) system for detecting diabetic macular edema (DME) within a diabetic retinopathy screening pathway. Their findings demonstrated that the AI-OCT system significantly reduced false-positive referral rates compared to standard fundus photograph-based screening, while maintaining high sensitivity for DME detection, thus suggesting its potential to alleviate the burden on specialist eye clinics.
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