June 12, 2026 · Critical care medicine · DOI: 10.1097/CCM.0000000000007226

Positive Pleural Fluid Cultures in the ICU: A 10-Year Population-Based Cohort Study of Prevalence, Microbial Characteristics, and Clinical Associations

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The study aimed to evaluate the prevalence and microbial characteristics of positive pleural fluid cultures in ICU patients, as well as their associations with clinical assessments and 90-day mortality. The findings revealed that while the overall rate of positive cultures was low (4.1%), suspected pleural infections significantly increased the likelihood of a positive culture, which in turn was associated with higher 90-day mortality. This suggests that pleural fluid culturing may be particularly beneficial in cases of suspected infection.

Símun I Arge, Søren P Frambo, Frederik M Nielsen, Bodil S Rasmussen, Hans L Nielsen, Kirstine K Søgaard, Olav L Schjørring

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