Clinical Prediction Models for Prognostication After Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

The authors aimed to evaluate the prognostic performance of existing clinical prediction models (CPMs) for neuroprognostication following out-of-hospital cardiac arrest (OHCA). They found that while several CPMs, including the OHCA and Cardiac Arrest Hospital Prognosis (CAHP) scores, demonstrated moderate accuracy in predicting poor functional outcomes, there was substantial heterogeneity among validation cohorts, which limits their clinical applicability for critical decisions like withdrawing life-sustaining therapy.