Regression of liver cirrhosis

The authors investigate the potential for regression in liver cirrhosis, traditionally viewed as a fixed end-stage condition, by examining how sustained control of its underlying causes can lead to significant architectural changes in the liver. They highlight the complexity of cirrhosis as a heterogeneous disease influenced by various cellular phenotypes and emphasize the need for improved measurement tools and therapies to effectively address its reversibility, especially in light of recent challenges in antifibrotic treatments.