June 20, 2026 · Journal of hepatology · DOI: 10.1016/j.jhep.2026.05.027

MRI-based prediction of very early recurrence within 1 year after resection of HCC: An international cohort study

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The study aimed to develop and validate MRI-based models for predicting very early recurrence of hepatocellular carcinoma (HCC) within one year after surgical resection, addressing the lack of reliable noninvasive prediction tools. By analyzing a large international cohort, the authors created two models (MERP-pre and MERP-post) that outperformed existing prognostic systems and effectively stratified patients into distinct risk groups based on their one-year recurrence-free survival. These findings suggest that the MERP models could enhance risk-stratified management of HCC by integrating readily available clinical and imaging data.

Hong Wei, Subin Heo, Yang Yang, Mengsi Li, Fangfang Fu, Tianyi Xia, Seung Soo Lee, Eun Sun Choi, Riccardo Sartoris, Jules Grégory, Christine Ying Kwok, Luna Wang, Junhan Pan, Yanyan Zhang, Roberto Cannella, Zhenru Wu, Yingyi Wu, Xinyuan Jia, Yuanan Wu, Yanshu Wang, Ting Duan, Ting Yang, Liuji Sheng, Chongtu Yang, Shi-Ting Feng, Ming Kuang, Hui-Chuan Sun, Yuancheng Wang, Meiyun Wang, Shenghong Ju, Victoria Chernyak, Jean-Charles Nault, Stephen Lam Chan, Jeong Min Lee, Cher Heng Tan, Wenzheng Li, Mustafa R Bashir, Feng Chen, Maxime Ronot, Bin Song, Hanyu Jiang

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