June 8, 2026 · JAMA internal medicine · DOI: 10.1001/jamainternmed.2026.1910

Rehospitalization and the Association of Postoperative Delirium With Cognitive Decline in Older Adults

Listen to this summary

This study aimed to determine whether the cognitive decline associated with postoperative delirium in older adults is mediated by illness and frailty, as indicated by recurrent hospitalizations. The findings revealed that while delirium was linked to greater cognitive decline and increased rehospitalization rates, rehospitalization did not significantly mediate the relationship between delirium and long-term cognitive decline. The authors suggest that further research is necessary to explore the underlying mechanisms connecting delirium to cognitive deterioration.

Tammy T Hshieh, Zachary J Kunicki, Tamara G Fong, Edward R Marcantonio, Eva M Schmitt, Guoquan Xu, Richard N Jones, Sharon K Inouye

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play