April 25, 2026 · Kidney international · DOI: 10.1016/j.kint.2026.03.015

Clinical and Histologic Predictors of Non-Diabetic Kidney Disease in Patients with Diabetes Mellitus

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The authors investigate the prevalence of non-diabetic kidney disease (NDKD) in patients with diabetes mellitus who undergo kidney biopsy, aiming to identify clinical and histologic predictors that increase the likelihood of detecting NDKD. Their analysis of over 49,000 biopsied patients reveals that NDKD is present in 58.8% of cases, highlighting the importance of kidney biopsy in this population and providing insights for nephrologists on when to perform biopsies based on specific clinical indications.

Tiffany N Caza, Vivek Charu, Dao-Fu Dai, Vicki G Davis, Frank Boyd, Lily Spenst, Patrick D Walker

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