Targeting B cells in immune-mediated kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
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The authors aim to evaluate the current evidence and identify research gaps regarding B cell-targeted therapies for immune-mediated kidney diseases, as discussed during a KDIGO Controversies Conference. They highlight the varying effectiveness and safety profiles of these therapies across different glomerular diseases, noting specific treatments like rituximab for membranous nephropathy and novel approaches for lupus nephritis. The authors emphasize the need for validated biomarkers and optimized treatment protocols to enhance patient outcomes.
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