April 26, 2026 · The American journal of medicine · DOI: 10.1016/j.amjmed.2026.04.021

Changes in High-Sensitivity Troponin I Dynamics Pre and Post Parturition are Phenotype Specific

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The authors aimed to investigate the dynamics of high-sensitivity troponin I (hs-cTnI) levels before and after delivery in women with different pregnancy phenotypes, specifically preeclampsia, hypertension, and normotensive controls. Their findings indicate that while hs-cTnI levels increase significantly post-delivery, the rise is most pronounced in preeclampsia, suggesting that delivery acts as a physiological "stress test" for cardiovascular health, with implications for maternal morbidity and future cardiovascular risk.

Yaxin Li, He S Yang, Zhengming Chen, Isla Racine, Damien Gruson, Allan S Jaffe, Zhen Zhao

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