Prenatal 17-Alpha-Hydroxyprogesterone Caproate Exposure in Twins and Childhood Outcomes: 14-Year Follow-Up of a Randomised Trial
Listen to this summary
The authors aimed to evaluate the long-term effects of prenatal exposure to 17-alpha-hydroxyprogesterone caproate (17-OHPC) compared to placebo on childhood outcomes in twins, specifically assessing aspects such as mortality, educational attainment, cognition, and behavior. The study followed children from the AMPHIA trial up to 14 years of age and found no significant differences in these outcomes between the two groups. Overall, the findings suggest that 17-OHPC exposure during pregnancy does not have a meaningful impact on child development or health in this population.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from BJOG : an international journal of obstetrics and gynaecology
View all →Mar 24, 2026 · BJOG : an international journal of obstetrics and gynaecology
Impaired Hearing and Systolic Blood Pressure as Potential Markers of Cerebral Infarction After Eclampsia: A Cross-Sectional Study
Mar 24, 2026 · BJOG : an international journal of obstetrics and gynaecology
Bariatric Surgery, Gestational Diabetes and Perinatal Outcomes: A Population-Based Study
Mar 16, 2026 · BJOG : an international journal of obstetrics and gynaecology
Prenatal Prescription Opioid Analgesic Exposure and Academic Performance in Third Grade Children: A Population-Based Cohort Study
Mar 16, 2026 · BJOG : an international journal of obstetrics and gynaecology
Comparative Efficacy of Elinzanetant Versus Other Non-Hormonal Pharmaceutical Therapies for the Treatment of Moderate-to-Severe Vasomotor Symptoms Associated With Menopause: A Network Meta-Analysis
Mar 14, 2026 · BJOG : an international journal of obstetrics and gynaecology
Laparoscopic Versus Robot-Assisted Sacrocolpopexy: A Systematic Review and Meta-Analysis
Mar 13, 2026 · BJOG : an international journal of obstetrics and gynaecology
One-Hour Plasma Glucose and Early Cardiometabolic Risk in Normoglycaemic Women With Polycystic Ovary Syndrome: A Retrospective Cross-Sectional Study
More in Obstetrics & Gynecology
View all →Mar 25, 2026 · The New England journal of medicine
A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide
Mar 24, 2026 · Human reproduction (Oxford, England)
Early pregnancy concentrations of pregnancy-associated plasma protein-A (PAPP-A) and insulin-like growth factor-1 (IGF-1) following frozen embryo transfer: secondary analyses from a randomized controlled trial
Mar 24, 2026 · Menopause (New York, N.Y.)
Targeted literature review of concepts related to women's experiences and perceptions of vasomotor symptoms associated with menopause
Mar 24, 2026 · Human reproduction (Oxford, England)
Human stem cell-based embryo models: innovation, ethics, and policy
Mar 24, 2026 · Human reproduction (Oxford, England)
Heat exposure during susceptible windows of spermatogenesis and sperm epigenetic age
Mar 24, 2026 · Human reproduction (Oxford, England)
How big is the time window for cell-free fetal DNA testing after pregnancy loss and which factors are associated with a successful result?
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
