BJOG : an international journal of obstetrics and gynaecology
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Association Between Proteinuria and Pregnancy Outcomes in Women With Preterm Pre-Eclampsia Undergoing Expectant Management: Secondary Analysis of Two Randomised Trials

Sep 18, 2026

The authors aimed to determine the association between proteinuria levels and pregnancy outcomes in women with preterm pre-eclampsia undergoing expectant management. They found that higher proteinuria levels correlated with shorter pregnancy latency and increased adverse maternal outcomes, while no significant association was observed with perinatal outcomes. The study suggests that proteinuria may provide valuable prognostic information for clinical decision-making in this population.

Population Prevalence and Incident HPA-1a Alloimmunisation in Pregnancy: A Prospective, Multi-Ethnic, Natural History Study

Sep 14, 2026

The authors aimed to determine the prevalence of higher risk for HPA-1a alloimmunisation and the development of foetal-neonatal alloimmune thrombocytopaenia (FNAIT) among a diverse cohort of pregnant women. The study found that only 1.7% of participants were of the HPA-1b/1b genotype, with a small percentage of those at higher risk developing anti-HPA-1a antibodies post-partum, highlighting the rarity of this condition and its varying prevalence among different racial and ethnic groups.

Pre-Procedure Predictors of Six-Month Survival After Fetoscopic Laser Ablation for Twin-Twin Transfusion Syndrome (TTTS): Retrospective Observational Study

Sep 3, 2026

The authors aimed to identify pre-procedure maternal, pregnancy, and fetal factors that predict survival until six months of age following fetoscopic laser ablation for twin-twin transfusion syndrome (TTTS). Their study found that short cervical length, early gestational age at intervention, and abnormal donor umbilical artery Doppler flow are significant predictors of survival outcomes, with survival rates improving over a 25-year period. These findings provide important insights for pre-procedural counseling in affected pregnancies.

A Uterus-Preserving Laparoscopic Technique for Cervicovaginal Agenesis With Functional Uterine Remnants

Sep 2, 2026

The authors aim to present a uterus-preserving laparoscopic technique for patients with cervicovaginal agenesis and functional uterine remnants, addressing the challenges of creating a neovagina while ensuring effective uterine drainage. They report successful restoration of menstrual drainage in seven patients, with no significant complications, although they caution that the presence of an accessible uterine cavity does not guarantee normal uterine function or reproductive outcomes. The study highlights the need for further research to evaluate fertility potential and long-term results of this approach.

Temporal Trends and Spatial Variation in Preterm Prelabour Rupture of Membranes: A Population-Based Study

Sep 1, 2026

The authors aimed to investigate the temporal trends and geographical distribution of preterm prelabour rupture of membranes (PPROM) in metropolitan France from 2015 to 2023. Their findings revealed an overall increasing incidence of PPROM, with notable geographical disparities and a temporary decrease in 2020, highlighting the need for targeted prevention strategies in high-risk areas. This study serves as a foundational analysis for further research into the environmental factors influencing PPROM incidence.

Vaginal Oestrogen Therapy for Postmenopausal Women Undergoing Prolapse Surgery: A Multicentre Double-Blind Randomised Placebo-Controlled Clinical Trial

Aug 28, 2026

The study aimed to determine whether vaginal oestrogen therapy improves outcomes for postmenopausal women undergoing prolapse surgery. Results indicated that women receiving vaginal oestrogen reported significantly greater subjective improvement in prolapse symptoms and better pelvic floor-related quality of life at 12 months compared to those receiving a placebo, although anatomical outcomes remained unchanged. The findings suggest that vaginal oestrogen could be considered as an adjunctive treatment option in the management of postmenopausal women undergoing primary prolapse surgery.

Added Value of Estimated Fetal Weight Growth Velocity to Doppler Evaluation for the Prediction of Perinatal Outcomes Among Foetuses With EFW < 10th Centile at Term: A Retrospective Cohort Study

Aug 26, 2026

The authors aimed to determine whether the growth velocity of estimated fetal weight (EFW) provides additional predictive value for adverse perinatal outcomes in term fetuses with EFW below the 10th centile, beyond standard Doppler evaluations. Their retrospective cohort study found that while slow EFW growth velocity was common and correlated with certain adverse indicators, it did not significantly improve the prediction of composite adverse outcomes compared to established Doppler and biometric criteria. Thus, the study questions the clinical utility of incorporating EFW growth velocity into routine assessments for this population.

High Versus Low Transvaginal Cerclage and Pregnancy Outcomes: A Secondary Analysis of the C-STICH Trial

Aug 21, 2026

The authors aimed to compare pregnancy outcomes between high and low transvaginal cerclage techniques in women at high risk of preterm birth. Their analysis of the C-STICH trial revealed no significant difference in pregnancy loss rates between the two techniques, but high vaginal cerclage was associated with a slight increase in mean gestational age and a lower incidence of births before 32 weeks.

Patient and Clinician Perspectives on Postpartum Thromboembolism Risk and Pharmacologic Thromboprophylaxis Use: A Qualitative Study

Aug 20, 2026

This qualitative study aimed to explore the information needs and perspectives of postpartum individuals and obstetric clinicians regarding the risk of venous thromboembolism (VTE) and the use of pharmacologic thromboprophylaxis after cesarean delivery. Findings revealed that while patients were generally informed about VTE risks and expressed a willingness to use prophylaxis despite some discomfort, both patients and clinicians identified gaps in education and the need for improved communication. Additionally, there was a shared recognition of the necessity for further research to refine VTE risk estimates and enhance thromboprophylaxis guidelines.

Vaginal Misoprostol Compared to Vaginal Dinoprostone for Induction of Labour: A Systematic Review and Meta-Analysis

Aug 19, 2026

This systematic review and meta-analysis aimed to compare the efficacy and safety of vaginal misoprostol versus vaginal dinoprostone for labor induction. The findings indicate that vaginal misoprostol is more effective in achieving vaginal births within 24 hours, reduces the need for oxytocin, and does not increase the rates of cesarean sections or adverse outcomes compared to dinoprostone. Additionally, lower doses of misoprostol (25 μg) may offer similar effectiveness with a reduced risk of uterine hyperstimulation.