Comparative Efficacy of Elinzanetant Versus Other Non-Hormonal Pharmaceutical Therapies for the Treatment of Moderate-to-Severe Vasomotor Symptoms Associated With Menopause: A Network Meta-Analysis
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The authors aimed to compare the efficacy of elinzanetant, a novel non-hormonal therapy, with other non-hormonal pharmaceutical treatments for alleviating moderate-to-severe vasomotor symptoms (VMS) associated with menopause. The network meta-analysis of 17 randomized controlled trials revealed that elinzanetant significantly reduced VMS frequency and severity compared to several other treatments, while also improving sleep disturbances, thereby supporting its effectiveness in managing VMS.
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