March 9, 2026 · JAMA internal medicine · DOI: 10.1001/jamainternmed.2026.0012

Cost-Related Medication Nonadherence After the Inflation Reduction Act

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The authors aimed to evaluate the impact of the Inflation Reduction Act's 2024 prescription drug provisions on cost-related medication nonadherence and healthcare-related financial strain among Medicare beneficiaries. Their analysis revealed a significant reduction in medication nonadherence among these beneficiaries following the reforms, particularly among those with multiple chronic conditions, while no meaningful changes were observed in financial strain. These findings suggest that the IRA's provisions may enhance chronic disease management and improve clinical outcomes for Medicare recipients.

Lucas X Marinacci, Stephen Mein, Benjamin N Rome, Rishi K Wadhera

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