March 23, 2026 · JAMA internal medicine · DOI: 10.1001/jamainternmed.2026.0102

Transesophageal Echocardiography During CPR in Patients With Out-of-Hospital Cardiac Arrest: The EXECT-CPR Randomized Clinical Trial

Listen to this summary

The authors aimed to determine whether transesophageal echocardiography (TEE) guidance during cardiopulmonary resuscitation (CPR) could improve outcomes in patients with nontraumatic out-of-hospital cardiac arrest compared to conventional CPR techniques. The study found no significant differences in the primary outcome of sustained return of spontaneous circulation or other secondary outcomes between the TEE-guided and conventional CPR groups, although the TEE group showed higher intra-CPR end-tidal carbon dioxide levels. These findings suggest that while TEE-guided CPR did not enhance clinical outcomes, it may offer hemodynamic benefits without increasing adverse events.

Sheng-En Chu, Chiao-Yin Cheng, Chih-Jung Chang, Hua Ho, Hsuan-An Chen, Chun-Hsiang Chan, Matthew H Ma, Chin-Ho Chang, Kuang-Chau Tsai, Kuan-Ming Chiu, Lee-Wei Chen, Wen-Chu Chiang, Jen-Tang Sun

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play