March 9, 2026 · JAMA internal medicine · DOI: 10.1001/jamainternmed.2025.8215

Cannabis and Mental Health: A Review

Listen to this summary

The authors review the relationship between cannabis use and mental health, aiming to clarify the benefits and risks associated with cannabis for individuals with mental health conditions. They find that while cannabis is commonly used to manage symptoms, there is low-certainty evidence supporting its efficacy, particularly for conditions like PTSD, anxiety, and depression, and significant risks of adverse effects, especially for vulnerable populations. The study emphasizes the need for clinicians to discuss these risks with patients, as cannabis use can exacerbate mental health issues and lead to cannabis use disorder.

Devan Kansagara, Garth E Terry, Chelsea K Ayers, Deepak C D'Souza

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play