March 23, 2026 · JAMA internal medicine · DOI: 10.1001/jamainternmed.2026.0190

Health Benefits, Costs, and Cost-Effectiveness of Jail-Based Hepatitis C Elimination Strategies

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The authors aimed to evaluate the health benefits, costs, and cost-effectiveness of jail-based interventions for hepatitis C virus (HCV) elimination among people who inject drugs. Their analysis found that a combined strategy of testing, treatment, and navigation services significantly reduced HCV infections and related deaths, achieving an incremental cost-effectiveness ratio of $11,000 per quality-adjusted life-year gained, which is well below typical cost-effectiveness thresholds. The study concludes that implementing these interventions in jails is a viable and cost-effective public health strategy.

Lin Zhu, Lora N Magaldi, Indrani A Wagh, Eliza R Ennis, Marissa B Reitsma, Danica E Kuncio, Eman Addish, Sandy R Varghese, Nathan W Furukawa, Amanda A Honeycutt, Yijie Chen, Benjamin P Linas, Joshua A Salomon

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