A phase II study in newly diagnosed stage III/IV epithelial ovarian cancer evaluating carboplatin/taxol/pembrolizumab in patients receiving neoadjuvant chemotherapy followed by pembrolizumab maintenance with or without olaparib
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This phase II study aims to evaluate the efficacy of combining carboplatin, paclitaxel, and pembrolizumab in patients with newly diagnosed stage III/IV epithelial ovarian cancer receiving neoadjuvant chemotherapy, followed by pembrolizumab maintenance with or without olaparib. The trial seeks to address the unmet need for improved treatment strategies that extend progression-free survival in this patient population, particularly given the high relapse rates associated with current standard therapies. The results may guide future clinical approaches for managing advanced epithelial ovarian cancer.
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