September 17, 2026 · The American journal of medicine · DOI: 10.1016/j.amjmed.2026.08.030

Metabolic Dysfunction-Associated Steatotic Liver Disease and Outcomes in Atrial Fibrillation

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The authors aimed to investigate the prognostic significance of metabolic dysfunction-associated steatotic liver disease (MASLD) in patients with established atrial fibrillation (AF). Their retrospective cohort study found that while MASLD did not affect all-cause mortality, it was associated with increased risks of major adverse cardiovascular events and chronic kidney disease. These findings suggest that MASLD may serve as a risk marker for morbidity in AF patients, though causality remains unestablished.

Pojsakorn Danpanichkul, Yanfang Pang, Kwanjit Duangsonk, Nithila Sivakumar, Primrose Tothanarungroj, Ahmad Anouti, Matheus Souza, Omar Y Mousa, Thomas G Cotter, Donghee Kim, Suthat Liangpunsakul, Chayakrit Krittanawong, Mazen Noureddin

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