Thoracentesis with pleural fluid cytology versus thoracoscopy with pleural biopsy for the diagnosis of malignant pleural effusion: a cost-effectiveness study
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This study investigates the cost-effectiveness of thoracentesis with pleural fluid cytology versus thoracoscopy with pleural biopsy for diagnosing malignant pleural effusion (MPE) in patients with prior or active malignancy. The findings suggest that thoracentesis is more cost-effective as an initial diagnostic strategy when the cytology sensitivity is above 27%, while thoracoscopy is favored for recurrent effusions after a negative thoracentesis.
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