Revascularization in Asymptomatic Carotid Artery Stenosis With Hemodynamic Impairment and Cognitive Outcomes: The CREST-H Substudy of the CREST-2 Randomized Clinical Trial
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The study aimed to determine whether revascularization of high-grade, asymptomatic internal carotid artery stenosis could improve cognitive function in patients with varying degrees of baseline cerebral hemodynamic impairment. The findings indicated no significant cognitive benefit from revascularization compared to intensive medical management alone over one year, suggesting that restoring blood flow does not alleviate cognitive dysfunction in this patient population.
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