September 22, 2026 · Lancet (London, England) · DOI: 10.1016/S0140-6736(26)00845-7

Current advancements in the care of peripheral arterial disease: modern approaches to medical, endovascular, and surgical treatment

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The authors review current advancements in the management of peripheral arterial disease (PAD), particularly focusing on the effectiveness of medical therapy, supervised exercise, and the judicious use of revascularization procedures. They aim to address how to optimize treatment strategies to reduce cardiovascular risks, improve quality of life, and minimize limb loss in patients with varying severity of PAD. The paper highlights the complexities of PAD management due to its multifaceted nature and the potential overuse of invasive interventions.

Riikka Tulamo, Andrew Bradbury, Caitlin W Hicks, Anders Gottsäter, Prem Chand Gupta, Ulrich Rother, Birgitta Sigvant, Robert Hinchliffe

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