September 18, 2026 · Lancet (London, England) · DOI: 10.1016/S0140-6736(26)01669-7

Precision prevention and early detection: framework for a new clinical cancer control pathway

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The authors explore how precision prevention and early detection (PPED) can improve cancer control by identifying individuals at elevated risk and tailoring interventions accordingly. They emphasize the importance of both escalating preventive care for high-risk individuals and de-escalating interventions for low-risk individuals, while also highlighting the need for a robust health-system infrastructure to support ongoing prevention efforts. The paper addresses the challenge of enhancing cancer survival rates through better screening and preventive strategies.

Timothy R Rebbeck

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