September 15, 2026 · European heart journal · DOI: 10.1093/eurheartj/ehag519

Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials

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The authors aimed to investigate the relationship between whole-grain consumption and cardiometabolic risk factors through a meta-analysis of randomized trials. They found that an increase of 48 g/day in whole-grain intake was associated with significant reductions in body weight, waist circumference, total cholesterol, and other cardiometabolic markers, particularly at intakes of approximately 60-100 g/day. However, the certainty of evidence varied across different outcomes, and data on higher intake levels were limited.

Sina Naghshi, Sevil Kiani, Alireza Ostadrahimi, Ahmad Jayedi, Majid Mobasseri, Sara Arefhosseini, Helda Tutunchi, Dagfinn Aune

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