August 27, 2026 · Fertility and sterility · DOI: 10.1016/j.fertnstert.2026.08.687

The VILOCITY Trial: Validating Incubators in the Lab, Optimizing Culture and Investigating BlasTulation Yield, a Randomized Control Trial (RCT)

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The VILOCITY Trial aimed to determine if using a benchtop incubator for embryo culture would enhance blastulation rates compared to a conventional box incubator in patients undergoing IVF. The study found no significant differences in blastulation rates, fertilization rates, or clinical outcomes between the two incubator types, suggesting that the choice of incubator does not meaningfully impact embryo development or subsequent pregnancy outcomes when other variables are controlled.

Blake Vessa, Francesca Barrett, Rosanna Pangasnan, Pablo Guzman Noriega, Nico Garrido, Christine Whitehead, Emre Seli, Marie Werner, Thomas Molinaro

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